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March 2022 – New Scientific Discovery
(Hint Not Diet or Exercise)
Are you struggling to lose weight no matter how much you diet or exercise? Turns out, it’s not your fault.
A 2022 study published in Nature Medicine of 52,000 women and men, the largest of its kind in humans, found just one common factor in every overweight man and woman. Low brown adipose tissue levels! They also found common in every skinny person were high brown adipose tissue levels.1
Brown adipose tissue (BAT) also know as brown fat, is not fat at all. Its not a fat storer but a fat shrinker. Its brown color comes from its densely packed mitochondria which work 24/7 to burn calories from your fat stores and the food you eat into pure, natural energy.
Even though BAT makes up a fraction of your weight, it can burn up to 300 times more calories than any other cell in your body!2
References:
1.https://www.nature.com/articles/s41591-020-1126-7
2.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768171/
8 clinically-proven ingredients that increase calorie-burning brown adipose tissue (BAT)
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Kamiya T, Nagamine R, Sameshima-Kamiya M, Tsubata M, Ikeguchi M, Takagaki K. The isoflavone-rich fraction of the crude extract of the Puerariae flower increases oxygen consumption and BAT UCP1 expression in high-fat diet-fed mice. Glob J Health Sci. 2012;4(5):147-155. Published 2012 Aug 12. doi:10.5539/gjhs.v4n5p147
Kamiya T, Takano A, Matsuzuka Y, et al. Consumption of Pueraria flower extract reduces body mass index via a decrease in the visceral fat area in obese humans. Biosci Biotechnol Biochem. 2012;76(8):1511-1517. doi:10.1271/bbb.120235
Xu JH, Liu XZ, Pan W, Zou DJ. Berberine protects against diet-induced obesity through regulating metabolic endotoxemia and gut hormone levels. Mol Med Rep. 2017;15(5):2765-2787. doi:10.3892/mmr.2017.6321
Wu L, Xia M, Duan Y, et al. Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans. Cell Death Dis. 2019;10(6):468. Published 2019 Jun 13. doi:10.1038/s41419-019-1706-y
Kunkel SD, Elmore CJ, Bongers KS, et al. Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease. PLoS One. 2012;7(6):e39332. doi:10.1371/journal.pone.0039332
Jung YC, Kim HW, Min BK, et al. Inhibitory Effect of Olive Leaf Extract on Obesity in High-fat Diet-induced Mice. In Vivo. 2019;33(3):707-715. doi:10.21873/invivo.11529
Oi-Kano Y, Kawada T, Watanabe T, et al. Oleuropein, a phenolic compound in extra virgin olive oil, increases uncoupling protein 1 content in brown adipose tissue and enhances noradrenaline and adrenaline secretions in rats. J Nutr Sci Vitaminol (Tokyo). 2008;54(5):363-370. doi:10.3177/jnsv.54.363
Sohn EJ, Kim JM, Kang SH, et al. Restoring Effects of Natural Anti-Oxidant Quercetin on Cellular Senescent Human Dermal Fibroblasts. Am J Chin Med. 2018;46(4):853-873. doi:10.1142/S0192415X18500453
Arias N, Picó C, Teresa Macarulla M, et al. A combination of resveratrol and quercetin induces browning in white adipose tissue of rats fed an obesogenic diet. Obesity (Silver Spring). 2017;25(1):111-121. doi:10.1002/oby.21706